检验医学与临床2016，Vol.13Issue(8)：1052-1054,3.DOI:10.3969/j.issn.1672-9455.2016.08.017
1～3月龄下呼吸道感染患儿致病菌与耐药状况研究
Study on pathogenic bacteria and drug resistance of infants aged 1-3 months old with lower respiratory tract infection
吴世园 1印海燕1
作者信息
- 1. 湖南省怀化市妇幼保健院检验科 418000
- 折叠
摘要
Abstract
Objective To analyze the distribution and drug resistance of pathogenic bacteria in infants aged 1-3 months old with lower respiratory tract infection .Methods A total of 291 infants aged 1-3 months old with low‐er respiratory tract infection in our hospital were selected as the research subjects and their sputum samples were col‐lected for conducting the microbial culture and drug sensitivity test by K‐B method .Results Among 291 samples , 216 strains of pathogenic bacteria were detected with the detection rate of 74 .2% ,in which Gram negative bacteria and Gram positive bacteria accounted for 78 .7% and 19 .4% respectively ,and fungi accounted for 1 .9% .Gram nega‐tive bacteria were dominated by Escherichia coli and Haemophilus influenzae ,which accounted for 25 .5% and 18 .5%respectively ,Gram positive bacteria were dominated by staphylococcus aureus and Streptococcus pneumoniae ,which accounted for 7 .8% and 6 .0% respectively .The resistant rates of Escherichia coli and Haemophilus influenzae to ampicillin and cefazolin were higher and lower to aztreonam and imipenem ,gatifloxacin and minocycline ,Staphylococ‐cus aureus and Streptococcus pneumoniae had higher resistance rate to clindamycin ,erythromycin ,lincomycin and gentamicin and lower resistance rates to ceftriaxone and gatifloxacin .Conclusion The main pathogenic bacteria cau‐sing lower respiratory tract infection in infants aged 1-3 months old are Gram negative bacteria .In the clinical thera‐py ,antibacterial drugs should be rationally selected according to the microbial culture results and their drug resistance rate data .关键词
下呼吸道感染/致病菌/耐药性Key words
lower respiratory tract infections/pathogenic bacteria/drug resistance引用本文复制引用
吴世园,印海燕..1～3月龄下呼吸道感染患儿致病菌与耐药状况研究[J].检验医学与临床,2016,13(8):1052-1054,3.
