检验医学与临床2016，Vol.13Issue(8)：1063-1064,2.DOI:10.3969/j.issn.1672-9455.2016.08.021
静脉注射丙种球蛋白改善小儿重症手足口病炎性因子水平的作用
Role of intravenous immunoglobulin globulin for improving inflammatory factor levels in children patients with severe hand,foot and mouth disease
赵秋剑1
作者信息
- 1. 陕西省宝鸡市中心医院检验科 721008
- 折叠
摘要
Abstract
Objective To investigate the role of intravenous immunoglobulin (IVIG) for improving the inflam‐matory factor levels in children patients with severe hand ,foot and mouth disease(HFMD) .Methods The retrospec‐tive analysis was adopted .The clinical data of 120 children patients with severe HFMD in our hospital were collected and the patients were divided into the conventional treatment group and IVIG group ,60 cases in each group .The con‐ventional treatment group was given the general treatment and symptomatic treatment ,while on this basis the IVIG group was added with IVIG .The changes of inflammatory factor levels were compared between before and after treatment .At the same time 60 children undergoing the healthy physical examination were selected as the control group .Results The TNF‐α,CRP and IL‐6 levels before treatment in the conventional treatment group and IVIG group were significantly increased compared with the control group ,the difference was statistically significant(P<0 .05);the TNF‐α,CRP and IL‐6 levels had no statistically significant differences between the conventional treatment group and the IVIG group (P>0 .05);the TNF‐α,CRP and IL‐6 levels after treatment in the IVIG group were sig‐nificantly decreased compared with the conventional treatment group(P<0 .05) .Conclusion IVIG for treating severe HFMD could effectively reduce the generation of inflammatory factors of TNF‐α,IL‐6 ,etc .and effectively promote patients to recover .关键词
丙种球蛋白/重症手足口病/炎性因子/儿童Key words
immunoglobulin/severe hand ,foot and mouth disease/inflammatory factors/children引用本文复制引用
赵秋剑..静脉注射丙种球蛋白改善小儿重症手足口病炎性因子水平的作用[J].检验医学与临床,2016,13(8):1063-1064,2.
