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腋窝转移性恶性黑色素瘤七例临床病理及误诊分析

刘静 张锐 曹鹏 朱正龙

临床误诊误治2016,Vol.29Issue(4):12-15,4.
临床误诊误治2016,Vol.29Issue(4):12-15,4.DOI:10.3969/j.issn.1002-3429.2016.04.004

腋窝转移性恶性黑色素瘤七例临床病理及误诊分析

Clinical and Pathological Misdiagnosis Analysis of 7 Cases of Axillary Metastatic Malignant Melanoma

刘静 1张锐 2曹鹏 1朱正龙1

作者信息

  • 1. 225400 江苏 泰兴,扬州大学附属泰兴市人民医院病理科
  • 2. 225400 江苏 泰兴,扬州大学附属泰兴市人民医院肿瘤放疗科
  • 折叠

摘要

Abstract

Objective To investigate the clinical and pathological characteristics of axillary metastatic malignant mel-anoma, and improve correct diagnosis rate of the disease. Methods Clinical and pathological data of 7 cases of axillary ma-lignant melanoma were analysed retrospectively. Results The average age of the 7 cases was 60. 1 years old. Only two cases were diagnosed correctly, and the other five cases were misdiagnosed as lymphoma, spindle cell sarcoma, malignant peripheral nerve sheath tumor, lung carcinoma, and Malignant neurofibrosarcoma. The 7 patients underwent radical surgery, and then were diagnosed by pathology and immunohistochemistry. S-100 protein was positive in all the cases, HMB-45 was positive in 2 cases. After surgical operation, 3 patients lost follow-up, and 1 died. Conclusion There are no special and typical clinical features of axillary malignant melanomas. The tumor cells are very complex and diverse. So they may be easily misdiagnosed. Pathological and clinical physicians should be aware of the possibility of the disease in the diagnosis, and should carefully asked about the history of the case and perform physical examinations. Pathological diagnosis should be made with the help of immunohistochemistry, special staining or electron microscopy.

关键词

黑色素瘤/腋窝/误诊/淋巴瘤/肉瘤/病理学,分子/免疫组织化学

Key words

Melanoma/Axillary/Misdiagnosis/Lymphoma/Sarcoma/Pathology, molecular/Immunohistochemistry

分类

医药卫生

引用本文复制引用

刘静,张锐,曹鹏,朱正龙..腋窝转移性恶性黑色素瘤七例临床病理及误诊分析[J].临床误诊误治,2016,29(4):12-15,4.

临床误诊误治

OACSTPCD

1002-3429

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