临床误诊误治2016，Vol.29Issue(4)：89-93,5.DOI:10.3969/j.issn.1002-3429.2016.04.030
宫颈癌容积调强弧形治疗与调强放疗技术对患者分次内误差的影响
Effect on Patients with Intrafractional Errors Resulting from Volumetric Modulated Arc Therapy and Step-and-shoot IMRT Techniques in Cervical Cancer Radiotherapy
摘要
Abstract
Objective To analyze the effect on patients with the intrafractional errors resulting from volumetric modu-lated arc therapy ( VMAT) and intensity modulated radiation therapy ( IMRT) techniques in cervical cancer radiotherapy. Methods Clinical data of 20 cases of cervical cancer diagnosed by pathological diagnosis in our center during October 2013 to July 2014 were analyzed according to the different methods of radiotherapy, and were divided into VMAT group and IMRT group ( n=10 each group) . All the patients with cervical cancer accepted kV-CBCT ( kilovoltage cone-beam computed tomo-graphy) scans after initial setup, correction and treatment with Elekta synergy accelerator. By acquiring kV-CBCT images and planned CT images, the errors of patients after initial setup were measured after correction and treatment on the X axis ( left-right, LR) , the Y axis ( superior-inferior, SI) and Z axis ( anterior-posterior, AP) , respectively. By the measurement of er-rors, the intrafractional errors of patients with cervical cancer in the radiotherapy were estimated and compared between the two groups. Results By using VMAT technique, the intrafractional errors of patients in the LR, SI and AP were less than that of IMRT group in three dimensional directions (P=0. 009;P=0. 008;P=0. 009). Abdominal pain occurred in 9 patients and acute radiation-induced enteritis occurred in 1 patient in the VMAT technique; abdominal pain occurred in 7 patients and acute radiation-induced enteritis occurred in 3 patient in the IMRT technique. Conclusion In cervical cancer radiotherapy, compared with IMRT technique, VMAT technique can achieve lower rate of intrafractional errors and can improve the accuracy of cervical cancer radiotherapy, which is worthy of clinical application.关键词
宫颈肿瘤/容积调强弧形治疗/调强放疗/千伏级锥形束CTKey words
Uterine cervical neoplasm/Volumetric modulated arc therapy/Intensity modulated radiation therapy/kV-CBCT分类
医药卫生引用本文复制引用
王恩阳,徐飞,贾明轩,曾越灿..宫颈癌容积调强弧形治疗与调强放疗技术对患者分次内误差的影响[J].临床误诊误治,2016,29(4):89-93,5.基金项目
国家自然科学基金资助项目（81201803) （）
