中南医学科学杂志2016，Vol.44Issue(1)：51-53,63,4.DOI:10.15972/j.cnki.43-1509/r.2016.01.013
cTnI 联合 NT-proBNP 对急性心肌梗死的早期诊断价值
Clinical Value of Combined Detection of Cardiac Troponin I and N-terminal Pro-brain Natriuretic Peptide in Early Diagnosis of Acute Myocardial Infarction
冷玉萍1
作者信息
- 1. 河北友爱医院心血管内科，河北 石家庄 050000
- 折叠
摘要
Abstract
Objective To explore the clinical value of combined detection of cardiac troponin I (cTnI) and N-ter-minal pro-brain natriuretic peptide (NT-proBNP NT-proBNP) in early diagnosis of acute myocardial infarction. Methods 71 patients with acute myocardial infarction delivered in our hospital served as the treatment group,and 67 healthy subjects served as the control. The blood plasma cTnI and NT-proBNP was detected. Result The cTnI and NT-proBNP of pa-tients in treatment group were significantly higher than that of patients in control (all P < 0. 001). The AMI positive detec-tion rate of combined detection of cardiac cTnI and NT-proBNP was significantly higher than that of detecting cTnI or NT-proBNP alone. The sensitivity and specificity of combined detection of cardiac cTnI and NT-proBNP was significantly higher than that of detecting cTnI or NT-proBNP alone (all P < 0. 001). Conclusion Combined detection of cardiac cTnI and NT-proBNP can monitor the progress of the disease timely and accurately,which can increase the sensitivity and specificity of the early diagnosis of acute myocardial infarction,decrease the mortality and disability of AMI and improve patients’ prog-nosis and life quality.关键词
肌钙蛋白Ⅰ/氨基末端脑钠肽前体/心肌梗死/急性/早期诊断Key words
cardiac troponin I/N-terminal pro-brain natriuretic peptide/acute myocardial infraction/early diagnosis分类
医药卫生引用本文复制引用
冷玉萍..cTnI 联合 NT-proBNP 对急性心肌梗死的早期诊断价值[J].中南医学科学杂志,2016,44(1):51-53,63,4.
