神经病学与神经康复学杂志2016，Vol.12Issue(1)：12-16,5.DOI:10.12022/jnnr.2016-0020
2015年视神经脊髓炎谱系疾病诊断标准国际共识解读
Comment on international consensus diagnostic criteria for neuromyelitis optica spectrum disorders, 2015
摘要
Abstract
(CNS) syndrome distinct from multiple sclerosis (MS). The discovery of highly specific ABSTRACTNeuromyelitis optica (NMO) is an idiopathic inflammatory central nervous system antiaquaporin-4 antibody as a diagnostic biomarker for NMO has enabled recognition of NMO and expanded the concept of neuromyelitis optica spectrum disorders (NMOSD). The International Panel for NMO Diagnosis (IPND) was convened to develop revised diagnostic criteria of NMOSD—International Consensus Diagnostic Criteria for NMOSD, 2015. In this new nomenclature, the individual definition of NMO is cancelled and classified into unified term NMOSD, which is stratified further by serologic testing (AQP4-immunoglobulin G-positive or -negative). One of the core clinical characteristics is necessarily required for patients with AQP4-immunoglobulin G-positive NMOSD. More stringent clinical criteria, with additional neuroimaging findings, is required for diagnosis of AQP4-immunoglobulin G-negative NMOSD or when serologic testing is unavailable. This paper presents the highlights of International Consensus Diagnostic Criteria for NMOSD, 2015, and gives some comments.关键词
视神经脊髓炎谱系疾病/诊断标准/指南/水通道蛋白 4Key words
Neuromyelitis optica spectrum disorders/Diagnostic criteria/Guideline/Aquaporin-4引用本文复制引用
张瑛,管阳太..2015年视神经脊髓炎谱系疾病诊断标准国际共识解读[J].神经病学与神经康复学杂志,2016,12(1):12-16,5.基金项目
国家自然科学基金项目（编号81230027）FUNDING/SUPPORT：National Natural Science Foundation of China (No.81230027) （No.81230027）
