生物技术通报2016，Vol.32Issue(4)：34-38,5.DOI:10.13560/j.cnki.biotech.bull.1985.2016.04.004
诱导多能干细胞在血液系统疾病中的研究进展
Research Progress on Induced Pluripotent Stem Cells in Hematopoietic Diseases
摘要
Abstract
Hematopoietic stem cell transplantation for the treatment of blood system diseases has been had great progress. However,due to the issues of limited donor and matching efficiency is not high,which seriously hindered its wide application in clinic. It is imperative to seek more secure,economical and effective resources of hematopoietic stem cell. Induced pluripotent stem cells can be differentiated into a variety of cells in vitro,especially deeper research on induced differentiation into hematopoietic stem cells in vitro. In this paper,iPS cells directed differentiation to hematopoietic stem cells in vitro and research progress on transplant are reviewed.关键词
造血干细胞移植/诱导多能干细胞/造血分化Key words
hematopoietic stem cell transplantation/induced pluripotent stem cells/hematopoietic differentiation引用本文复制引用
范荻,孙筱放..诱导多能干细胞在血液系统疾病中的研究进展[J].生物技术通报,2016,32(4):34-38,5.基金项目
国家自然科学基金项目(U1132005),国家自然科学基金项目(31171229) （U1132005）
