实用医学杂志2016，Vol.32Issue(5)：735-738,4.DOI:10.3969/j.issn.1006-5725.2016.05.015
缺血性脑卒中急性期超敏C－反应蛋白水平变化与进展性卒中的相关性
The correlation study between the level of high-sensitivity C-reactive protein in acute phase of ischemic ;stroke and progressive stroke
摘要
Abstract
Objective To study the correlation of the level of high-sensitivity C-reactive protein (Hs-CRP) in the acute phase of ischemic stroke and progressive stroke. Methods 101 patients with acute ischemic stroke were collected. Serum Hs-CRP of all patients were measured at 24 hours after admission , the onset of 48 hours, the onset of 72 hours by latex enhanced immune turbidity method. According to their serum Hs-CRP lev-els, the patients were divided into the group of Hs-CRP sustained growth (n = 35) and the group of non Hs-CRP sustained growth (n = 66). The NIHSS scores were assessed on two groups of patients , Logistic regression analysis was made to screen the related factors of Hs-CRP increase and the possible risky factors for progressive ischemic stroke. Results There was a significant difference of serum Hs-CRP level between the two groups (P <0.001). The incidence of progressive stroke in the group of Hs-CRP sustained growth was significantly higher than that in the group of non Hs-CRP sustained growth (χ2 = 32.710, P < 0.001). Logistic regression analysis showed blood glucose , white blood cell count , triglyceride level and NIHSS scores at admission were associated with sustained growth of Hs-CRP and the factors that they included Hs-CRP sustained growth , admission NIHSS scores, diabetes mellitus and pulmonary infection were regarded as independent risk factors. Conclusion The sustained growth of Hs-CRP in the acute phase of ischemic stroke is an independent predictor of progressive stroke.关键词
卒中/炎症/超敏C反应蛋白/进展性卒中Key words
Stroke/Inflammation/High-sensitivity C reactive protein/Progressive stroke引用本文复制引用
姚涛,任明山,李淮玉..缺血性脑卒中急性期超敏C－反应蛋白水平变化与进展性卒中的相关性[J].实用医学杂志,2016,32(5):735-738,4.基金项目
安徽省医学科研课题 （）
