陕西科技大学学报（自然科学版）2016，Vol.34Issue(2)：81-86,6.
BBD 设计-效应面法优化 SnCl 4改性液体骨胶胶粘剂的制备
Optimization of preparation of bone glue adhesive material modified by SnCl4 using BBD design and response surface
摘要
Abstract
Bone glue adhesive w as modified by Sn4+ coordination ,and response surface method was used to optimize the experiment .According to the design principle of Box-Behnken De-sign ,on the basis of single factor experiments ,the response surface method of three factors with three levels were employed ,the freezing point and viscosity were taken as reponses val-ue to analyze the significance and interaction of the three factors such as the amount of SnCl4 ,the amount of carbamide ,the amount of lauryl sodium sulfate ,through the regression model ,the optimal reaction conditions and the predicted values were calculated by the regres-sion model ,and the optimum reaction condition were verified by repeated experiments .Ex-periment results show that the optimum synthetic conditions and the predicted results are in good agreement with the experimental results .The optimal synthesis condition were amount of SnCl4 1 .27 g ,amount of carbamide 0 .79 g ,amount of lauryl sodium sulfate 0 .44 g ,the predictive value for reponse were freezing point 4 .4 ℃ ,viscosity 1 .902 Pa・s .关键词
骨胶胶粘剂/效应面法/优化工艺/配位Key words
bone glue adhesive/response surface/optimize/coordination分类
化学化工引用本文复制引用
苏秀霞,卜海艳,崔明,吕檬夷,赵擎霄..BBD 设计-效应面法优化 SnCl 4改性液体骨胶胶粘剂的制备[J].陕西科技大学学报（自然科学版）,2016,34(2):81-86,6.基金项目
陕西省科技厅工业科技攻关计划项目 （）
