现代妇产科进展2016,Vol.25Issue(4):257-260,4.DOI:10.13283/j.cnki.xdfckjz.2016.04.005
宫腔镜检查对Ⅱ型子宫内膜癌患者腹腔细胞学结果及预后的影响
Effect of hysteroscopy on peritoneal cytology and prognosis in patients with type Ⅱ en-dometrial carcinoma
陈娇 1孔为民 1宋丹 1焦思萌 1李霞 1张同庆1
作者信息
- 1. 首都医科大学附属北京妇产医院妇瘤科,北京 100006
- 折叠
摘要
Abstract
Objective:To investigate the effect of hysteroscopy on peritoneal cytology and prognosis in patients with type Ⅱ endometrial carcinoma, and to investigate the safety of hysteroscopy in the diagnosis of endometrial carcinoma. Methods:The clinical and pathological datas of 84 patients with type Ⅱ endometrial carcinoma were retrospectively analyzed in our hospital from June. 2001 to June. 2010. According to the preoperative diagnosis methods,it was divided into the dilatation and curettage( DC) group with 52 cases and the hysteroscopy group with 32 cases. The clinical and pathological characteristics and the positive rate of peritoneal cy-tology were compared in two groups. The effect of hysteroscopy on the prognosis of patients with type Ⅱ endometrial carcinoma were analyzed. Results:There were no significant difference in age,pathological type,clinical stage,muscular invision,accessory and lymph node metastasis ( P>0 . 05 ) . The positive rate of peritoneal cytology were 37 . 5%( 12/32 ) and 17 . 3%( 9/52 ) in hysteroscopy group and DC group,respectively,which was statistically significant (χ2=4. 308,P=0 . 036 ) . The 5 year overall survival rate ( OS ) and progression free survival ( PFS ) were 56. 8% vs 69. 2% and 50. 7% vs 67. 9%,respectively,and there were no significant difference between hysteroscopy group and DC group ( P=0 . 329;P=0 . 424 ) . Conclusions:The use of hysteroscopy in diagnosis of type Ⅱ endometrial carcinoma increases the risk of peritoneal dis-semination of cancer cells,but the long-term survival may not be affected.关键词
子宫恶性肿瘤/子宫浆液性腺癌/透明细胞癌/癌肉瘤/宫腔镜/腹腔/腹水细胞/预后Key words
Uterine neoplasm/Uterine serous adenocarcinoma/Clear cell carcinoma/Carcinosarcoma/Hysteroscopy/Peritoneal washings/Prognosis分类
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陈娇,孔为民,宋丹,焦思萌,李霞,张同庆..宫腔镜检查对Ⅱ型子宫内膜癌患者腹腔细胞学结果及预后的影响[J].现代妇产科进展,2016,25(4):257-260,4.