中国组织工程研究2016，Vol.20Issue(4)：486-491,6.DOI:10.3969/j.issn.2095-4344.2016.04.006
严重痛风性膝关节炎的膝关节表面置换
Total knee replacement for severe gouty knee arthritis
摘要
Abstract
BACKGROUND: The number of patients undergoing total knee replacement due to severe gouty arthritis is increasing rapidly in recent years, and the ages of patients also present younger and younger. However, its clinical efficacy remains controversial, and it is lack of retrospective systematic analysis. OBJECTIVE: To assess the clinical efficacy of total knee replacement for severe gouty knee arthritis from several aspects, such as pain, function, quality of life and complications. METHODS: From January 2006 to January 2015, 17 patients (20 knees) with severe knee gouty arthritis received total knee replacement in Department of Orthopedics of Nanjing General Hospital of Nanjing Military Region of Chinese PLA. They underwent knee joint surface replacement with posterior cruciate ligament, and patel a was not replaced. Posterior stabilized prosthesis was used. Al patients were successful y fol owed up postoperatively. The Hospital for SpecialSurgery Knee Score, range of motion of the knee, Visual Analogue Scale score and SF-36 scale scores were determined before and after replacement and during final fol ow-up. RESULTS AND CONCLUSION: Patients were fol owed up for 1-9 years. No serious complications occurred during and after replacement. The Hospital for Special Surgery Knee Score, range of motion of the knee, Visual Analogue Scale score and SF-36 scale scores were significantly higher after replacement and during final fol ow-up than those before replacement (P < 0.001). X-ray films showed good prosthesis position, satisfactory limb alignment without radiolucent lines or loosing. These findings verified that total knee replacement was considered as the final way to treat the severe gouty knee arthritis; its short-term clinical effect is significant, but systematic anti-uric acid, prevention and treatment of complications, pain control, function exercising, and healthy mood maintenance were needed to get a better long-term clinical efficacy.关键词
骨科植入物/人工假体/痛风性关节炎/膝关节表面置换/随访研究分类
医药卫生引用本文复制引用
刘康,郭国栋,赵建宁..严重痛风性膝关节炎的膝关节表面置换[J].中国组织工程研究,2016,20(4):486-491,6.基金项目
江苏省临床医学科技专项基金(BL2012002)；南京市科研基金(201402007)@@@@ the Clinical Medical Science and Technology Foundation of Jiangsu Province, No. BL2012002 （BL2012002）
the Scientific Research Foundation of Nanjing City, No.201402007 （）
