中国组织工程研究2016，Vol.20Issue(4)：517-521,5.DOI:10.3969/j.issn.2095-4344.2016.04.011
骨水泥螺钉强化固定伴骨质疏松腰椎滑脱症的稳定性及椎间融合
Stability and interbody fusion of augmented pedicle screws with bone cement for lumbar spondylolisthesis accompanied with osteoporosis
摘要
Abstract
BACKGROUND: In lumbar spondylolisthesis patients with severe osteoporosis, screw is easily loose and pul s out during reposition, or loss of reduction and internal fixation failure easily occur after repair. Therefore, it is very important to elevate the intensity of pedicle screw fixation during repair. At present, few studies concern application of bone cement screw enhancement technology in lumbar spondylolisthesis patients with osteoporosis. OBJECTIVE: To investigate the clinical value of augmented pedicle screw with polymethylmethacrylate for lumbar spondylolisthesis accompanied with osteoporosis. METHODS: From June 2009 to June 2011, 27 patients suffering from lumbar spondylolisthesis accompanied with osteoporosis were included in this retrospective study. These patients received augmented pedicle screw with polymethylmethacrylate. The levels of disability and pain were evaluated by Oswestry Disability Index and visual analog scale. The internal fixation and fusion were evaluated by radiological findings. Al complications were recorded. RESULTS AND CONCLUSION: Al cases were fol owed up for 15-37 months. Oswestry Disability Index and visual analog scale scores were significantly better in final fol ow-up than that pre-treatment (P < 0.05). Imaging results revealed that bone cement tightly connected to bone interface. The position of screw and bone cement was good. Symptomatic bone cement leakage was not found. No fixation failure was detected during final fol ow-up. Al patients achieved interbody fusion. These results suggested that polymethylmethacrylate bone cement could increase the gripping force of the pedicle screw in osteoporotic vertebral body. It is safe and effective to treat spondylolisthesis accompanied with osteoporosis with augmented pedicle screws. Satisfactory fixation stability and interbody fusion can be obtained.关键词
骨科植入物/脊柱植入物/腰椎滑脱症/骨质疏松/椎弓根螺钉/钉道强化/骨水泥/聚甲基丙烯酸甲酯/椎间融合分类
医药卫生引用本文复制引用
姚珍松,丁金勇,唐永超,陈康,江晓兵,梁德,晋大祥,庄洪,张顺聪,杨志东..骨水泥螺钉强化固定伴骨质疏松腰椎滑脱症的稳定性及椎间融合[J].中国组织工程研究,2016,20(4):517-521,5.基金项目
卫生部医药卫生科技发展研究中心资助课题(W2014ZT256, W2012ZT0)；广东省卫生厅医学科研基金(2014B2014175)@@@@ a grant from Medical and Health Science and Technology Development Research Center of Ministry of Health, No. W2014ZT256, W2012ZT0 （W2014ZT256, W2012ZT0）
the Medical Science and Technology Foundation of Department of Health of Guangdong Province, No.2014B2014175 （）
