现代医药卫生2016，Vol.32Issue(6)：836-838,841,4.DOI:10.3969/j.issn.1009-5519.2016.06.012
慢性肾脏病患者贫血与铁代谢的相关性研究
Correlation between anemia and iron metabolism in patients with chronic kidney disease
张静 1杨俊伟1
作者信息
- 1. 南京医科大学第二附属医院肾内科，江苏南京210003
- 折叠
摘要
Abstract
Objective To explore the degree of anemia and iron metabolism disorder in the patients with chronic kidney disease(CKD)and their relationship. Methods Totally 240 patients with initially diagnosed CKD in the nephrology department of our hospital from January 2012 to October 2015 were selected and divided into the CKD stage 1-5 according to the estimated value of glomerular filtration rate(eGFR). The data of hemoglobin(Hb),red blood cell count(RBC),hematokrit(Hct),serum iron (SI),total iron binding capacity(TIBC),serum transferrin saturation(TSAT) and serum ferritin(SF) were collected and the cor-relation between the anemia detection indicators with iron metabolic detection indicators was analyzed. Results The different degree of anemia existed among the CKD 5 stages. The Hb,RBC,Hct levels had statistical differences between the CKD stage 3-5 with the CKD stage 1-2(P<0.05). The SI and TSAT levels in the CKD stage 3 were decreased compared with the CKD stage 1 (P<0.05),while the SI and TSAT levels in the CKD stage 4-5 were decreased compared with the CKD stage 1-2 (P<0.05). The SI and TSAT levels in the CKD stage 3-5 were positively correlated with the Hb and Hct levels (P<0.05). Conclusion The different degree of anemia exists among the CKD stage 1-5. Anemia is closely correlated with iron metabolism in CKD patients ,the lower the eGFR value,the more severe the anemia and iron metabolic disorder.关键词
肾疾病/慢性病/贫血,缺铁性/铁代谢障碍/肾小球滤过率Key words
Kidney diseases/Chronic disease/Anemia, iron-deficiency/Iron metabolism disorders/Glomeru-lar filtration rate引用本文复制引用
张静,杨俊伟..慢性肾脏病患者贫血与铁代谢的相关性研究[J].现代医药卫生,2016,32(6):836-838,841,4.
