协和医学杂志2016，Vol.7Issue(2)：81-87,7.DOI:10.3969/j.issn.1674-9081.2016.02.001
卵巢衰老过程中的月经改变
Menstrual Cylc icity Change in Ovair an Aging
何仲 1林守清 2陈蓉 2陈瑛 3高洪莲 4乌正赉5
作者信息
- 1. 中国医学科学院 北京协和医学院 继续教育学院，北京100730
- 2. 中国医学科学院 北京协和医学院 北京协和医院妇产科，北京100730
- 3. 首都医科大学附属北京友谊医院妇产科，北京100050
- 4. 滨州医学院附属医院临床医学实验中心，山东滨州256603
- 5. 中国医学科学院 北京协和医学院 基础医学研究所流行病及统计学系，北京100005
- 折叠
摘要
Abstract
Objective To observe the alterations of each menstrual factor in ovarian aging .Methods The data were obtained from one-year observation of a prospective cohort involving 323 healthy women in the age of 30-54 years in a community in Beijing .Menstrual diary was kept and serum level of follicle-stimulating hor-mone ( FSH) was tested .The participants were divided into groups based on age , FSH level , and stages of repro-ductive aging.Alterations of length of menstrual cycle (LMC), length of menstrual period , and menstrual volume were analyzed in each group .Results Age:the mean LMC extended after the age of 40 years, obviously after 48, and peaked with (67.04 ±36.77) days in≥52-year-old group.The mean length of menstrual period did not vary much with age .However , the variation of mean length of menstrual period gradually increased with age after 44 years old, peaked in 50-to 51-year-old group.The menstrual volume scores were approximately stable between 38 and 47 years of age , with a peak of (45.06 ±93.54) in48 -to 49-year-old group and a minimum of (15.87 ± 13.81) in≥52-year-old group.FSH level:LMC increased with elevation of FSH levels .There was no signifi-cant difference in the mean length of menstrual period among FSH level groups , but the variation of length of menstrual period was maximum in 20<FSH≤40U /L group.The maximum mean menstrual volume score was (30.69 ±31.84), observed in 10<FSH≤15 U/L group, while the minimum was (17.38 ±24.38 ) in FSH>40U /Lgroup .Stages of reproductive aging:the length of menstrual period and menstrual volume scores among each stage showed no statistically significant difference ( P>0.05 ) .Co nclusions The LMC altered significant-ly in ovarian aging , which could be used as staging criteria of reproductive aging .The length of menstrual period and menstrual volume are also showing some characteristic changes , possibly of some clinical values .关键词
卵巢衰老/月经周期长度/月经经期/月经量Key words
ovarian aging/length of menstrual cycle/menstrual period/menstrual volume分类
医药卫生引用本文复制引用
何仲,林守清,陈蓉,陈瑛,高洪莲,乌正赉..卵巢衰老过程中的月经改变[J].协和医学杂志,2016,7(2):81-87,7.
