中国医疗设备2016，Vol.31Issue(2)：25-30,6.DOI:10.3969/j.issn.1674-1633.2016.02.006
基于MRM的小鼠脑模板创建的研究进展
Recent Advances in the Research of the Establishment of the MRM-based Mouse Brain Template
摘要
Abstract
The high resolution magnetic resource microcopy(MRM)has been widely used in mouse brain neuroimaging study. The mouth brain template and atlas are the tools essential to the mouse brain neuroimaging study. The mouth brain is characterized by its small volume and subtle microscopic changes, which creates dififculty for the establishment of the brain template and atlas. Nowadays many domestic and overseas’ researchers have focused on setting up different kinds of mouse brain templates. This paper ifrst introduced the imaging principle and imaging collection methods of MRM and discussed the strategies to optimize MRM. Secondly, the paper discussed basic elements of the mouse brain template construction, such as comparison of templates, data acquisition, registration algorithms, andetc. Finally, the paper introduced the fundamental application of the mouse brain template in the research and treatment of diseases such as Alzheimer’s disease and Huntington’s disease.关键词
脑图谱/脑模板/磁共振显微成像/图像配准Key words
brain atlas/brain template/magnetic resonance microscopy/image registration分类
医药卫生引用本文复制引用
付振荣,林岚,张柏雯,宾光宇,高宏建,吴水才..基于MRM的小鼠脑模板创建的研究进展[J].中国医疗设备,2016,31(2):25-30,6.基金项目
北京市自然科学基金（7143171）资助。 （）
