摘要
Abstract
Objective To observe the curative effect of seretide (salmeterol 50ug and fluticasone propionate 500ug) on patients with severe/very severe chronic obstructive pulmonary disease (COPD) at stable stage. Methods 42 cases of such patients were divided into two groups (the control group and the treatment group) randomly. The control group were given routine treatment. The treatment group were added with inhaled seretide 50/500 (1 puff twice daily ) to routine treatment. Forced expiratory volume in 1 second (FEV1), FEV1%pre, six-minute walk distance (6-MWD), and St George's respiratory questionnaire (SGRQ) score were measured and recorded before treatment,and at 1 months,3 months, 6 months after treatment beginning. Results At all the treatment time point, FEV1, FEV1% pre, 6-MWD, and SGRQ in treatment group were superior to those in control group. All difference between the two groups were significant( <0.05). Conclusion Inhaled seretide 50/500 can significantly improve lung function, movement tolerance and life quality of the patients with severe/very severe stable COPD.关键词
沙美特罗替卡松(舒利迭)/COPD/肺功能/生存质量Key words
Salmeterol/fluticasone propionate (seretide)/Chronic obstructive pulmonary disease (COPD)/Lung function/Life quality
