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西地那非治疗小儿先天性心脏病合并重度肺动脉高压的疗效分析

孙式荣 吕凤俊 李宁

中国社区医师2016,Vol.32Issue(12):28-28,30,2.
中国社区医师2016,Vol.32Issue(12):28-28,30,2.DOI:10.3969/j.issn.1007-614x.2016.12.14

西地那非治疗小儿先天性心脏病合并重度肺动脉高压的疗效分析

Curative effect analysis of sildenafil in the treatment of children with congenital heart disease associated with severe pulmonary arterial hypertension

孙式荣 1吕凤俊 1李宁1

作者信息

  • 1. 271100山东省莱芜市莱城区人民医院
  • 折叠

摘要

Abstract

Objective:To investigate the clinical curative effect analysis of sildenafil in the treatment of children with congenital heart disease associated with severe pulmonary arterial hypertension.Methods:70 cases of children with congenital heart disease associated with severe pulmonary arterial hypertension were divided into two groups randomly.Patients in the control group were given conventional treatment,while patients in the observation group were given sildenafil on the basis of the conventional treatment.The hemodynamics and NT-proBNP of the two groups before and after treatment were compared.Results:The mRAP, SaO2,CI,NT-ProBNP levels of the two groups after treatment were lower than those before treatment,and the differences were statistically significant(P<0.05).After treatment,the mRAP,SaO2,CI,NT-ProBNP improvement of the observation group were better than those of the control group,and the differences were statistically significant(P<0.05).Conclusion:Sildenafil in the treatment of children with congenital heart disease combined with severe pulmonary arterial hypertension had significant clinical curative effect and could improve the cardiac function of children.

关键词

西地那非/先天性心脏病/重度肺动脉高压

Key words

Sildenafil/Congenital heart disease/Severe pulmonary arterial hypertension

引用本文复制引用

孙式荣,吕凤俊,李宁..西地那非治疗小儿先天性心脏病合并重度肺动脉高压的疗效分析[J].中国社区医师,2016,32(12):28-28,30,2.

中国社区医师

1007-614X

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