中国社区医师2016，Vol.32Issue(12)：71-72,2.DOI:10.3969/j.issn.1007-614x.2016.12.43
重症监护病房噬血细胞淋巴组织细胞增生症临床分析
Clinical analysis of hemophagocytic lymphohistiocytosis of patients in the intensive care unit
郝燕1
作者信息
- 1. 458000河南省鹤壁市鹤壁煤业公司总医院血液内科
- 折叠
摘要
Abstract
Objective:To observe the risk factors of early death of patients with hemophagocytic lymphohistiocytosis(HLH). Methods:71 patients with HLH were selected in the intensive care unit.The 28 days mortality rate and risk factors were analyzed by univariate and multivariate.Results:The 28 days totality mortality rate and hospitalized mortality rate were respectively 38%and 68%.The relevant risk factors of increasing 28 days mortality rate included sequential organ failure(ICU scoring,P<0.001) and age increasing(P=0.03).The relevant risk factors of increasing hospitalized mortality rate were ICU admission score high-risk sequential organ failure(P<0.01),age increasing(P=0.04),lymphoma sample HLH or unexplained HLH(P<0.01).Conclusion:Organ failure is the most important reason in early death risk factors of adult ICU HLH patients.Using early specific cytotoxic treatment,controling basic diseases may prevent the occurrence of organ failure and early death.关键词
噬血细胞淋巴组织细胞增生症/成人/ICU/死亡率/危险因素Key words
Hemophagocytic lymphohistiocytosis/Adult/ICU/Mortality rate/Risk factors引用本文复制引用
郝燕..重症监护病房噬血细胞淋巴组织细胞增生症临床分析[J].中国社区医师,2016,32(12):71-72,2.
