中国比较医学杂志2016，Vol.26Issue(3)：81-85,5.DOI:10.3969.j.issn.1671-7856.2016.03.016
提高大鼠子宫内膜异位症建模成功率的新方法
A new method for improving the success rate of the establishment of endometriosis models in rats
李龙卫 1王艳云 1陈琦 1王亚萍 1韩璐1
作者信息
- 1. 大连医科大学附属妇产医院暨大连市妇幼保健院,辽宁大连 116033
- 折叠
摘要
Abstract
Objective To provide ideal endometriosis animal models for research new treatment methods. Methods 64 Sexual mature without pregnant SD rats who has regular oestrous cycle were underwent operation that autologous endometrium were transplanted to peritoneum and subcutaneous with lancet gently cut tissue of where to transplant in the rut, and compared the model of peritoneum and subcutaneous after 4 weeks.Results The general success rate of autologous endometrium transplantation in rat estrus was 93.3%,and the peritoneum transplantation success rate was 51.7%, subcutaneous was 88.3%, the difference of the two place transplantation has statistical significance. Compare the two parts of volume of endometriosis,there was no statistically significant difference.Conclusion Using the lancet to establish the endometriosis model has a high success rate, and subcutaneous model is better than peritoneum.关键词
子宫内膜异位症/模型/动物/动情期/啮齿Key words
Endometriosis/Model/animal/Estrus/Rodentia分类
医药卫生引用本文复制引用
李龙卫,王艳云,陈琦,王亚萍,韩璐..提高大鼠子宫内膜异位症建模成功率的新方法[J].中国比较医学杂志,2016,26(3):81-85,5.
