中国药房2016，Vol.27Issue(8)：1013-1016,4.DOI:10.6039/j.issn.1001-0408.2016.08.02
参芪扶正注射液联合化疗用于非小细胞肺癌的药物经济学评价
Pharmacoeconomics Evaluation of Shenqi Fuzheng Injection Combined with Chemotherapy for Non-small Cell Lung Cancer
刘小亚 1张学斌 2黄文华 1胡海棠 3朱文涛4
作者信息
- 1. 中国中药协会中药药物经济学专业委员会，北京 100101
- 2. 北京康派特医药科技开发有限公司，北京 100101
- 3. 丽珠集团利民制药厂，广东韶关 512028
- 4. 丽珠集团医学研究中心，广东珠海 519020
- 折叠
摘要
Abstract
OBJECTIVE:To evaluate the economic value of Shenqi fuzheng injection combined with chemotherapy vs. chemo-therapy alone for non-small lung cancer(NSCLC),and to provide reference for drug payment and clinical treatment. METHODS:By prospective cohort design,516 patients with non-small cell lung cancer from 11 hospitals were selected as subjects according to the sale distribution of Shenqi fuzheng injection in district and hospital;267 cases of Shenqi fuzheng injection combined with che-motherapy and 249 cases of chemotherapy alone formed naturally according the clinical therapy plan. The cost-effectiveness and cost-utility analysis were conducted using FACT-L score,KPS score and ZPS score as effect index,QALYs as effectiveness index observation period of 21 d. RESULTS:5 dimensions FACT-L score:the patients of Shenqi fuzheng injection combined with chemo-therapy group could be effectively improved,and the cost-effectiveness ratio was lower than chemotherapy alone group;KPS score:the cost-effectiveness ratio of Shenqi fuzheng injection combined with chemotherapy group was lower than chemotherapy alone group (1 632.44 vs. 11 145.30),and incremental cost-effectiveness ratio was 448.69. ZPS score:Shenqi fuzheng injection combined with chemotherapy group was lower than chemotherapy alone(-17 398.77 vs. 384 513.00). Shenqi fuzheng injection combined with chemotherapy group was lower than chemotherapy alone group in average cost per 1 QALYs(1 313 326 yuan vs. 13 374 365 yuan). CONCLUSIONS:Compared with chemotherapy alone group,Shenqi fuzheng injection combined with chemo-therapy can effectively improve the quality of life,and it is worth of spending more money on Shenqi fuzheng injection from the perspective of the pharmacoeconomics.关键词
参芪扶正注射液/非小细胞肺癌/成本-效果分析/成本-效用分析Key words
Shenqi fuzheng injection/Non-small cell lung cancer/Cost-effectiveness analysis/Cost-utility analysis分类
医药卫生引用本文复制引用
刘小亚,张学斌,黄文华,胡海棠,朱文涛..参芪扶正注射液联合化疗用于非小细胞肺癌的药物经济学评价[J].中国药房,2016,27(8):1013-1016,4.
