冻干重组人脑利钠肽联合左西孟旦治疗急性心力衰竭的临床观察OA北大核心CSTPCD
Clinical Observation of rhBNP Combined with Levosimendan in the Treatment of Acute Heart Failure
目的：观察冻干重组人脑利钠肽联合左西孟旦治疗急性心力衰竭的临床疗效与安全性，考察该联合用药对患者血清尿酸（UA）与脑钠肽（BNP）水平的影响。方法：68例急性心力衰竭患者依据抽签法随机分为观察组与对照组，各34例。两组患者均给予常规治疗，在此基础上对照组患者给予左西孟旦注射液5 ml加入0.9％氯化钠注射液45 ml中持续微泵注射：开始后第1 h内泵注速率为12μg/（kg·min），之后以0.5μg/（kg·min）的速率持续给药23 h；观察…查看全部>>
OBJECTIVE:To observe clinical efficacy and safety of rhBNP combined with levosimendan in the treatment of acute heart failure,and to investigated the effects of drug combination on serum UA and BNP levels. METHODS:68 patients with acute heart failure were randomly divided into observation group and control group,with 34 cases in each group. Both groups re-ceived routine treatment;control group was additionally given Levosimendan injection 5 ml added into 0.9…查看全部>>
曹俊雄;朱志军;吴丹宁
解放军第117医院心内科，杭州 310000解放军第117医院心内科，杭州 310000解放军第117医院心内科，杭州 310000
医药卫生
冻干重组人脑利钠肽左西孟旦联合用药急性心力衰竭尿酸脑钠肽
rhBNPLevosimendanDrug combirationAcute heart failureUABNP
《中国药房》 2016 (8)
1091-1093,3
评论