中国药房2016，Vol.27Issue(12)：1596-1599,4.DOI:10.6039/j.issn.1001-0408.2016.12.04
某院氯吡格雷在脑梗死二级预防中的使用合理性分析
Analysis of Clopidogrel Rational Use in Patients with Cerebral Infarction Secondary Prevention in A Hospital
摘要
Abstract
OBJECTIVE:To provide reference for improving the clopidogrel rational use in cerebral infarction secondary preven-tion. METHODS:Medical cases of 471 patients with acute cerebral infarction in neurology department in a hospital from 2013 to 2014 were retrospective surveyed to collect the utilization rate of clopidogrel and the combination of clopidogrel with proton pump inhibitors(PPIs)and aspirin,and the rationality was analyzed. RESULTS:The utilization rate of clopidogrel in cerebral infarction secondary prevention was 93.84%;the combination rate with PPIs was 52.49%,of which,51.72% had no drug selection or com-bined treatment basis;the combination rate with aspirin was 40.72%,cardiogenic cerebral infarction accounted for only 3.9%, non-cardiogenic cerebral infarction accounted for 96.1%,and recurrence of cerebral infarction in high-risk patients accounted for 31.11%. CONCLUSIONS:Clopidogrel in patients with cerebral infarction secondary prevention is widely used in the hospital,has high combination rate with PPIs and aspirin and low guide compliance rate. Clopidogrel should be enhanced pharmacy services, comply with evidence based medicine and improve the rationality of medication.关键词
氯吡格雷/脑梗死/二级预防/合理使用Key words
Clopidogrel/Cerebral infarction/Secondary prevention/Rational use分类
医药卫生引用本文复制引用
孙银香,刘梓健,张建萍..某院氯吡格雷在脑梗死二级预防中的使用合理性分析[J].中国药房,2016,27(12):1596-1599,4.基金项目
广东省医学科研基金立项课题(No.A2013636) （No.A2013636）
