中国药房2016，Vol.27Issue(12)：1677-1679,3.DOI:10.6039/j.issn.1001-0408.2016.12.31
双参胶囊的质量标准提高研究
Study on Improvement of Quality Standard of Shuangshen Capsule
摘要
Abstract
OBJECTIVE:To improve the quality standard of Shuangshen capsule. METHODS:TLC was conducted for the qual-itative identification of Curcumnae radix and Rehmannia glutinosa in the preparation. HPLC was used for the content determination of salvianolic acid B in the preparation:the column was Diamonsil C18(2)with mobile phase of acetonitrile-0.1% H3PO4(22:78, V/V) at a flow rate of 0.5 ml/min,detection wavelength was 286 nm,column temperature was 30 ℃,and the injection volume was 2 μl. RESULTS:The TLC spots of C. radix and R. glutinosa were clear and well separated;the linear range of salvianolic ac-id B was 0.0792-0.792 μg(r=0.9999);RSDs of precision,stability and reproducibility tests were lower than 1%;recovery was 100.71%-101.82%(RSD=0.50%,n=6). CONCLUSIONS:The established standard can be used for the quality control of Shuang-shen capsule.关键词
双参胶囊/丹酚酸B/薄层色谱法/高效液相色谱法Key words
Shuangshen capsule/Salvianolic acid B/TLC/HPLC分类
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崔小敏,李芳,李凡,王卫锋..双参胶囊的质量标准提高研究[J].中国药房,2016,27(12):1677-1679,3.
