中国药业2016，Vol.25Issue(1)：10-12,13,4.
肿瘤放射及化学治疗所致恶心呕吐的药物治疗研究现状
Drug Treatment of Antiemetic in Cancer Chemotherapy Plus Radiotherapy
胡钰 1罗洁丽 1黄艳芳 1李璐 1吴柳婷1
作者信息
- 1. 武汉科技大学附属普仁医院药学部，湖北 武汉 430081
- 折叠
摘要
Abstract
Objective To analyze the mechanism of nausea and vomiting caused by cancer chemotherapy plus radiotherapy and review various antiemetic mechanism. Methods To conduct retrospective studies by clinical trials and literatures, and to review the current re-searches on various types of antiemetic drugs, clinical application and progress. Results 5-hydroxytryptamine-3 ( 5-HT3 ) serotonin re-ceptor antagonists and neurokinin-1 receptor antagonist had good curative effects on acute vomiting, palonosetron and aprepitant were much more better for delayed emesis and combined with dexamethasone could increase efficacy. Conclusion Currently 5-HT3 receptor antagonist on acute vomiting is relatively positive, and if combined with NK-1 receptor antagonist and dexamethasone, can increase its efficacy.关键词
肿瘤放化疗/恶心呕吐/止吐药物/合理用药Key words
cancer chemotherapy plus radiotherapy/nausea and vomiting/antiemetics/reasonable application分类
医药卫生引用本文复制引用
胡钰,罗洁丽,黄艳芳,李璐,吴柳婷..肿瘤放射及化学治疗所致恶心呕吐的药物治疗研究现状[J].中国药业,2016,25(1):10-12,13,4.
