中国药业2016，Vol.25Issue(1)：13-16,17,5.
伤科消肿颗粒处方提取工艺优选
Optimization Study on Extracting Technology of Shangkexiaozhong Granules
摘要
Abstract
Objective To optimize the extracting technology conditions of shangkexiaozhong Granules. Methods Orthogonal design was used to optimize the extraction conditions, with the content of multi-target ingredients such as the extraction of volatile oil, total solid, content of paeoniflorin and chlorogenic acid as comprehensive evaluation indexes. Results The optimum extraction conditions were as follows:take a certain amount of mint extract with water;the volatile oil content was 75. 3% by this way;take the mint medical and the other 14 medicinal materials extracted with water for 2 times, the extraction percentage of Paeoniflorin and chlorogenic acid were 79. 8% and 83. 3%;the quantity of dry paste was 16. 49 g per formula;then concentrated water-decocted liquid to be 1. 15 on rela-tive density;added ethanol to 60% ( g/g );then kept them to be in cold storage and standing by 12 h;reduced pressure and concen-trated the supernatant, with the rate of transfer -remaining were 80% and 74%, and the quantity of dry paste was 10. 01 g per for-mula. Conclusion The Optimization of extraction process is simple, stable and feasible. The results provide the scientific experimental basis for determining the technology conditions of Shangkexiaozhong Granules.关键词
伤科消肿颗粒/正交试验/提取工艺Key words
Shangkexiaozhong Granules/Orthogonal Test/extracting process分类
化学化工引用本文复制引用
李海英,刘武,刘吉成..伤科消肿颗粒处方提取工艺优选[J].中国药业,2016,25(1):13-16,17,5.基金项目
2013年广西壮族自治区卫生厅中壮瑶药制剂研发类课题，项目编号GZZJ13－07。 （）
