中国药业2016，Vol.25Issue(2)：32-33,34,3.
替格瑞洛对经皮冠状动脉介入术后预后效果的影响
Ticagrelor on Prognosis Efficacy after Percutaneous Coronary Intervention
陈建玲 1谈晓侠 1刘会玲1
作者信息
- 1. 西安医学院第二附属医院急诊内科，陕西 西安 710000
- 折叠
摘要
Abstract
Objective To study the efficacy of ticagrelor on prognosis for patients with acute coronary syndrome after percutaneous coronary intervention. Methods 60 patients with acute coronary syndrome treated by percutaneous coronary intervention in the hospital during the period from January 2014 to February 2015 were divided into the control group (clopidogrel) and the observation group (ticagrelor) according to the random number method,30 cases in each group. The index changes of platelet aggregation and myocardial enzyme spectrum on pre- and post-operation,and the incidence of cardiac adverse events and bleeding events during the 6 months follow-up in the two groups were observed. Results Compared with the control group,the maximum platelet aggregation rate(MPAR) and P2Y12 reactivity unit,creatine kinase MB(CK-MB)and troponin(cTnI)were significantly reduced on post-operation in the ob-servation group( P < 0. 05);the incidence of cardiac adverse events were obviously decreased in the observation group( P < 0. 05). Conclusion Ticagrelor can significantly reduce the platelet aggregation after percutaneous coronary intervention for patients with acute coronary syndrome,decrease the incidence of cardiac adverse events,and improve the patients′ prognosis quality.关键词
替格瑞洛/氯吡格雷/急性冠状动脉综合征/经皮冠状动脉介入术Key words
ticagrelor/clopidogrel/acute coronary syndrome/percutaneous coronary intervention分类
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陈建玲,谈晓侠,刘会玲..替格瑞洛对经皮冠状动脉介入术后预后效果的影响[J].中国药业,2016,25(2):32-33,34,3.
