中国药业2016，Vol.25Issue(3)：7-9,3.
高效抗逆转录病毒治疗艾滋病的生存时间及临床疗效分析
Study of Survival Time and Clinical Efficacy of Highly Active Antiretroviral Therapy for HIV/AIDS
摘要
Abstract
Objective To study the survival time, treatment effect and Influence factors of highly active antiretroviral therapy for the HIV/AIDS patients. Methods 3 100 cases of HIV/AIDS patients admitted in Guigang were collected as the research object, all pa-tients received HAART and adopted COX proportional hazards model to analyze the survival factors and the risk factors that influenced the effect of HAART. Results In the 3100 cases of patients, 146 cases of HIV infection received TCM treatment, accounting for 4. 71%;56. 00% suffered weight loss, 35. 81% with persistent fever;19. 37% zoster;11. 58% persistent diarrhea;7. 50% with dyspha-gia. 190 cases died, accounting for 6. 13% ; 76 cases stopped medication, accounting for 2. 45%; 527 cases were lost, accounting for 17. 00%;2 307 cases continued treatment, accounting for 74. 42%. Multivariate analysis showed that treatment begin CD4 + T cell count level, opportunistic infections occur when the number of types of treatment, the average monthly number of medication leakage as the in-fluential factors of the highly active antiretroviral therapy ( P ﹤ 0. 05 ) . Conclusion HAART AIDS treatment has ideal efficacy. During the course of treatment effective measures to monitor changes in patients with CD4+ T and opportunistic infection should be taken, drug education should be strengthened, and dynamic understanding of the patient should be achieved to make timely adjustment of the treatment.关键词
艾滋病/高效抗逆转录病毒/生存时间/影响因素/疗效Key words
HIV/HAART/survival time/influencing factors/efficacy分类
医药卫生引用本文复制引用
吕日英,李健龙,覃雄林,朱宇佳,覃琼芬,付少萍,李仕雄,许超宇,江波..高效抗逆转录病毒治疗艾滋病的生存时间及临床疗效分析[J].中国药业,2016,25(3):7-9,3.基金项目
广西贵港市科学研究与技术开发计划，项目编号贵科学攻关12090280。 （）
