摘要
Abstract
Objective To study the efficacy of Deanxit treatment for patients with post-stroke depression. Methods 80 patients with post-stroke depression were randomized into the control group ( routine treatment ) and the observation group ( based on the routine treatment, addition to the Deanxit ) according to the random number method, 40 patients per group. The changes of Hamilton Depression Scale ( HAMD ) , National Institute of Health Stroke Scale ( NIHSS ) , Barthel index ( BI ) , and the plasma levels of norepinephrine ( NE ) , Dobaamine ( DA ) , 5-hydroxytryptamine ( 5-HT ) on pre- and post-treatment, and clinical efficacy and adverse reactions in the two groups were compared. Results Compared with the control group, the scores of HAMD and NIHSS were significantly decreased and the BI scores were obviously increased on post-treatment in the observation group ( P ﹤ 0. 05 );the plasma levels of NE, DA, 5-HT were significantly increased on post-treatment in the observation group ( P ﹤ 0. 05 ); the total effective rate was significant improved in the observation group ( P ﹤ 0. 05 ); there were no serious adverse reactions in the two groups during the treatment period. Conclusion Deanxit can significantly improve the neurological function and depression symptoms for patients with post-stroke depression, and im-prove the daily life ability.关键词
黛力新/脑卒中后抑郁/神经功能/日常生活能力Key words
Deanxit/post-stroke depression/neurological function/daily life ability分类
医药卫生
