中国医院用药评价与分析2016，Vol.16Issue(2)：159-161,3.DOI:10.14009/j.issn.1672-2124.2016.02.006
丙戊酸钠及氯硝西泮治疗迟发性运动障碍的疗效观察
Observation on Efficacy of Sodium Valproate and Clonazepam in Treatment of Tardive Dyskinesia
胡垒 1王立广2
作者信息
- 1. 厦门市仙岳医院神经内科，福建厦门 361012
- 2. 厦门市仙岳医院门诊，福建厦门361012
- 折叠
摘要
Abstract
OBJECTIVE:To probe into the efficacy and adverse reactions of sodium valproate and clonazepam in treatment of tardive dyskinesia (TD).METHODS:123 cases with TD were divided into observation group and control group via the random number table .The observation group were treated with sodium valproate and clonazepam , the control group received placebo vitamin B 6 .The effects of before and after 2, 4, 8 weeks were determined via abnormal involuntary movement scale ( AIMS ) .The efficacy and adverse reactions in patients were observed .RESULTS:After treatment with sodium valproate and clonazepam , scores of AIMS after 2, 4, 8 weeks were significantly decreased than before in observation group, which was better than the control group, with statistically significant difference (P<0.05).The effective rate of TD was 90.00%in observation group, while in control group, it was lower than 10.00%, with statistically significant difference (P<0.05).There was no obvious adverse reactions between two group pf patients .CONCLUSIONS:Sodium valproate and clonazepam in treatment of TD is safe and effective , it is worthy of clinical promotion .关键词
迟发性运动障碍/丙戊酸钠/氯硝西泮Key words
TD/Sodium valproate/Clonazepam分类
医药卫生引用本文复制引用
胡垒,王立广..丙戊酸钠及氯硝西泮治疗迟发性运动障碍的疗效观察[J].中国医院用药评价与分析,2016,16(2):159-161,3.
