摘要
Abstract
OBJECTIVE:To investigate the clinical efficacy of ulinastatin in treatment of septic shock .METHODS:280 cases with septic shock admitted into the First People's Hospital of Bijie from Dec .2012 to Dec.2014 were selected to be divided into two groups via the random number table , with 140 cases in each.The control group were treated with conventional treatment while the observation group additionally received ulinastatin based on the control group;the number of multiple organ dysfunction , death toll , length of stay in ICU , patient's recovery time , application time of anti-infective drugs and treatment cost were compared between two group of patients .RESULTS:In observation group , the number of multiple organ dysfunction were 64 cases(45.71%), death toll were 40 cases(28.57%), length of stay in ICU were (10.97 ±3.16) d, patient's recovery time were (6.32 ±0.45) d and treatment costs were (3.51 ±0.12) ten thousand yuan;while in control group these were 106 cases(75.71%), 52 cases(37.14%), (16.47 ±3.28) d, (8.57 ±0.73) d, (4.22 ±0.16) ten thousand yuan;there were statistically significance between two group of patients (P<0.05).The application time of anti-infective drugs in two groups were 7 d, with no statistically significant difference (P>0.05). CONCLUSIONS:Ulinastatin in treatment of septic shock can improve the clinical efficacy , significantly decrease the death toll of patients , and has essential clinical application value .关键词
乌司他丁/感染性休克/疗效Key words
Ulinastatin/Septic shock/Efficacy分类
医药卫生