肿瘤药学2016，Vol.6Issue(1)：78-80,3.DOI:10.3969/j.issn.2095-1264.2016.01.18
舒血宁注射液对恶性肿瘤患者血浆D-二聚体水平的影响
Effects of Shuxuening Injection on the Level of Plasma D-dimer in Patients with Malignant Tumor
刘建利 1杨玲 1杜秀平 1韩正祥1
作者信息
- 1. 徐州医学院附属医院肿瘤科，江苏 徐州，221002
- 折叠
摘要
Abstract
Objective To investigate the effects of Shuxuening Injection on the plasma D-dimer level of patients with malignant tumor. Methods 170 cases of patients with malignant tumor whose plasma D-dimer level were higher than the normal value were selected and di-vided into the observation group and the control group through a randomized controlled method, 85 cases in each. The observation group was given intravenous drip of Shuxuening injection once a day anticoagulant therapy, while the control group was given 4000 U of low molecular weight heparin sodium (enoxaparin) through subcutaneous injection, once a day. Both groups were treated for 10 days. The plasma D-dimer levels of both groups were detected before and after treatment. Results The plasma D-dimer levels of 170 cases of malignant tumor patients were decreased in different degrees after treatment. The plasma D-dimer levels of patients in the observation group and the control group decreased 52.65﹪and 54.11﹪respectively. No significant difference was found between the two groups before and after treatment (P﹥0.05). The incidence of adverse reactions in the observation group was 4.7﹪, which was significantly lower than that of the control group (25.9﹪, P﹤0.01). Conclusion Shuxuening Injection could significantly decrease the plasma D-dimer level of patients with malignant tumor, im-prove the hypercoagulable state, and lower the possibility of thrombogenesis.关键词
舒血宁/低分子肝素钠/恶性肿瘤/D -二聚体/血栓形成Key words
Shuxuening/Lowmolecularweightheparin/Malignanttumor/D-dimer/Thrombosis分类
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刘建利,杨玲,杜秀平,韩正祥..舒血宁注射液对恶性肿瘤患者血浆D-二聚体水平的影响[J].肿瘤药学,2016,6(1):78-80,3.
