中国现代中药2016，Vol.18Issue(3)：362-365,4.DOI:10.13313/j.issn.1673-4890.2016.3.024
不同粉碎度三七粒度分布和皂苷类成分溶出曲线研究
Study on Different Particle Diameters and Dissolution Profiles of Panax notoginseng
摘要
Abstract
Objective:To compare the particle size distribution and dissolution curves of cellwall-broken pieces of notoginseng,notoginseng common powder,notoginseng micropowder and notoginseng particles.Methods:The particle size distribution of cellwall-broken pieces of notoginseng,notoginseng common powder,notoginseng micropowder and notoginseng particles was detected.HPLC method was used for determination of three saponins including ginsenoside Rg1 and Rb1 , notoginsenoside R1 ,the dissolution curves were drawn.Results:The particle size distribution d(0.9)of cell-broken pieces of notoginseng,notoginseng common powder,notoginseng micropowder and notoginseng particles were 51.543,124.142, 27.760 and 107.539 μm,respectively.The dissolution rates exceeded 85% within 15 min.Conclusion:The dissolution curves of three saponins including ginsenoside Rg1 and Rb1 ,notoginsenoside R1 of cellwall-broken pieces of notoginseng, notoginseng common powder,notoginseng micropowder and notoginseng particles were similar.关键词
三七/中药破壁饮片/细粉/粒度分布/溶出曲线Key words
Panax notoginseng/cellwall-broken pieces of traditional Chinese medicine/common powder/particle size distribution/dissolution curves引用本文复制引用
白宗利,乐智勇,卢翠敏,万薇,陈华师,董婧婧,许冬瑾..不同粉碎度三七粒度分布和皂苷类成分溶出曲线研究[J].中国现代中药,2016,18(3):362-365,4.基金项目
广东省创新型企业院线提升计划项目(2013B07032007) （2013B07032007）
