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黄芪多糖对树突状细胞形态和功能影响研究进展

边亚彬 张景艳 王磊 王旭荣 张康 王学智 孟嘉仁 李建喜

动物医学进展2016,Vol.37Issue(4):86-89,4.
动物医学进展2016,Vol.37Issue(4):86-89,4.

黄芪多糖对树突状细胞形态和功能影响研究进展

Progress on Effects of Astragalus Polysaccharides on Morphology and Function of Dendritic Cells

边亚彬 1张景艳 1王磊 1王旭荣 1张康 1王学智 1孟嘉仁 1李建喜1

作者信息

  • 1. 中国农业科学院兰州畜牧与兽药研究所/甘肃省中兽药工程技术研究中心,甘肃兰州 730050
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摘要

Abstract

Dendritic cells(DCs)are the most efficient among the antigen-presenting cells.Because DCs play key roles in immune response and function,DCs are becoming the hot topics in the study of immunology. Polysaccharide is an important component of Astragalus,and it is comprised of uronic acid,fructose,arabi-nose,galacturonic acid.Astragalus polysaccharides have immunomodulatory,anti-tumor,anti-stress and an-tioxidant effects.The immune function of Astragalus polysaccharide is the main point for Astragalus all the time.It has been proved that Astragalus polysaccharide can promote the maturation of DCs,by doing that the immune responses are regulated.The paper reviewed the effects of Astragalus polysaccharides on the antigen-presenting ability of DCs from the changes of morphology and function of DCs,the maturation of DCs and the expressions of DC surface molecular markers(CD80,CD86,CD83)and cytokines.

关键词

黄芪多糖/树突状细胞/细胞因子

Key words

Astragalus polysaccharide/dendritic cell/cytokine

分类

农业科技

引用本文复制引用

边亚彬,张景艳,王磊,王旭荣,张康,王学智,孟嘉仁,李建喜..黄芪多糖对树突状细胞形态和功能影响研究进展[J].动物医学进展,2016,37(4):86-89,4.

基金项目

国家自然科学基金项目(31472233);公益性行业(农业)科研专项(201303040);公益性研究所基本科研费 ()

动物医学进展

OA北大核心CSTPCD

1007-5038

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