湖南中医药大学学报2016，Vol.36Issue(4)：25-27,3.DOI:10.3969/j.issn.1674-070X.2016.04.006
精液中SCF/c-kit值在肾虚男性不育辨证中的价值
The Value of SCF/c-kit in Semen of Infertile Male with Nephrasthenia Syndrome
摘要
Abstract
Objective To evaluate the value of SCF/c-kit in the diagnosis for male infertility with kidney deficiency, and to provide experimental references of the theory to the kidney stores the essence and controls reproductivity. Methods 45 infertile males with kidney deficiency were selected and 30 fertile men were used as control. SCF in seminal plasma was determined by ELISA. The relative expression of c-Kit was detected by real-time PCR, and the relative expression quantity was caculated. Results There is no difference of SCF concentration between the two groups (P>0.05). Compared with fertile men, the forward movement of sperm in infertile men with kidney deficiency was decreased obviously (P<0.01), and relative expression of c-kit was significantly increased (P<0.05). Conclusion Kidney deficiency is closely related to sperm motility and the relative expression quantity of c-Kit in sperm., which can be as indicators for infertile male with kidney deficiency. This study provides scientific basis for the theory of kidney storing the essence and controlling reproductivity.关键词
男性不育/肾虚证/干细胞因子/原癌基因蛋白质/弱精/精液Key words
male infertility/nephrasthenia syndrome/stem cell factor/c-kit/asthenospermia/semen分类
医药卫生引用本文复制引用
张芳,刘建荣,马月宏,丁彩云,尹海珍,高嵩丹..精液中SCF/c-kit值在肾虚男性不育辨证中的价值[J].湖南中医药大学学报,2016,36(4):25-27,3.基金项目
山西省卫生厅科研课题(201201061)。 （201201061）
