摘要
Abstract
Objective:To explore the relationships between balance function and cognition function in patients with Alzheimer's disease(AD) .Methods:Eighty AD patients were recruited and measured by Berg balance scale(BBS)and Montreal cognitive assessment(MoCA)to evaluate balance function and cognition function respectively ,and divided into three groups according to the scores of BBS including balance disfunctiongroup(n=19) ,impaired balance group (n=27) ,normal balance group(n= 34) .Results:AD patients with balance disfunction had lower scores of MoCA than those with impaired balance(d=1 5.1 ,P<0 0.01)or normal balance patients(d=3 .47 ,P<0 .001) ,while the former lower than the later(d=1 9.8 ,P<0 0.1) .AD patients with balance disfunction also had lower scores of atten‐tion /calculation(d=0 6.3 ,P<0 0.5)or visuospatial /executive function(d=1 .00 ,P<0 0.01)compared with those normal balance AD patients ,and decreased subscale score of visuospatial/executive function(d=0 5.4 ,P<0 0.5)com‐pared with those impaired balance AD patients .with impaired balance had lower subscale scores of visuospatial/exec‐utive function(d=0 5.1 ,P<0 0.5)than those AD patients with normal balance .The scores of BBS was positively re‐lated with scores of MoCA(r=0 4.35 ,P<0 0.1) ,subscale score of attention /calculation(r=0 2.26 ,P<0 0.5) ,and visuospatial/executive function(r=0 3.55 ,P<0 0.1) .The subscale score of static balance of BBS had a positive corre‐lation with scores of MoCA(r=0 3.94 ,P<0 0.01) ,subscale score of attention /calculation(r=0 2.23 ,P<0 0.5) ,and visuospatial/executive function(r=0 3.14 ,P<0 0.1) .The subscale score of dynamic balance of BBS had positively correlated with scores of MoCA(r=0 4.27 ,P<0 0.01) ,subscale score of attention /calculation(r=0 2.55 ,P<0 0.5) , visuospatial/executive function(r=0 3.57 ,P<0 0.1) or orientation(r=0 2.40 ,P< 0 0.5) .Conclusion:The damaged balance function should associate with the impaired cognition ,especially attention /calculation and visuospatial /exec‐utive function in AD patients .关键词
阿尔茨海默病/平衡功能/认知功能/Berg平衡量表/蒙特利尔认知评估量表Key words
Alzheimer's disease/Balance function/Cognitive function/BBS/MoCA分类
医药卫生
