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放疗联合免疫治疗的抗肿瘤免疫机制研究进展

刘超 吴世凯

军事医学2016,Vol.40Issue(4):353-355,359,4.
军事医学2016,Vol.40Issue(4):353-355,359,4.DOI:10.7644/j.issn.1674-9960.2016.04.022

放疗联合免疫治疗的抗肿瘤免疫机制研究进展

Advances in antitumor immune mechanisms of radiotherapy in combination with immunotherapy

刘超 1吴世凯2

作者信息

  • 1. 安徽医科大学解放军307临床学院,北京 100071
  • 2. 军事医学科学院附属医院放疗科,北京 100071
  • 折叠

摘要

Abstract

As a significant treatment for tumors, radiotherapy is often considered a local therapy.However, an increasing number of researches indicate that reasonable radiation dose schedules can improve the tumor environment, induce immunogenic tumor cell death, provide in situ vaccine, and stimulate systemic antitumor effect.Meanwhile, immunotherapy can enhance the effect induced by radiotherapy, which has been proved in preclinical studies and is widely investigated in clinical studies.This review focuses on the immune response and mechanisms of radiotherapy, and advances in the application of radiotherapy in combination with immunotherapy.

关键词

放射治疗/免疫治疗/肿瘤

Key words

radiotherapy/immunotherapy/neoplasms

分类

医药卫生

引用本文复制引用

刘超,吴世凯..放疗联合免疫治疗的抗肿瘤免疫机制研究进展[J].军事医学,2016,40(4):353-355,359,4.

军事医学

OA北大核心CSCDCSTPCD

1674-9960

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