摘要
Abstract
Objective: To evaluate the risk factors and countermeasures of infection in patients with on-pump coronary artery bypass grafting (OPCAB). Methods: 235 patients undergone OPCAB from January 2013 to September 2013 were selected. According to the occurrence of postoperative infection, patients were divided into infected group (n =32) and uninfected group (n = 203). Using single factor analysis method and the analysis of Logistic multivariate regression analysis, the risk factors of postoperative infection and the corresponding countermeasures were analyzed. Results: Single factor analysis showed that age, course of the disease, cardiac function, nutritional status, trachea of invasive operation, the application of antimicrobial agents, the length of hospital stay, and smoking are associated with postoperative infection in OPCAB (P< 0.05). Logistic multivariate regression analysis results showed that age (OR = 9.684,95%CI: 2.378 ~ 16.452), course of the disease (OR =9.828,95%CI:2.554 ~17.628), cardiac function (OR = 7.841,95%CI1.958~12.256), nutritional status (OR =7.967,95%CI:2.016~13.748), trachea of invasive operation (OR =9.927,95%CI:2.728~18.157), antimicro-bial application (OR =9.763,95%CI:2.455~17.428)and length of hospital stay (OR =9.702,95%CI:2.382~16.828)were independent factors associated with postoperative infection in OPCAB (P<0.05). Conclusions:The postoperative infection risk factors of OPCAB are age, course of the disease, cardiac function, nutritional status, trachea of invasive operation, antimicrobial application and the length of hospital stay. The extended time of antimicrobial application, the shortened the length of hospital stay, the reduced the invasive operation of trachea, the improved nutritional status and cardiac functions, and the strengthened and extended interventions to the older are all beneficial to prevent the postoperative infection in OPCAB patients.关键词
体外循环/不停跳冠脉搭桥术/感染/危险因素/对策Key words
Extracorporeal circulation/On-pump Coronary Artery Bypass Grafting/Infection/Risk factors/Countermeasures分类
医药卫生
