现代医药卫生2016，Vol.32Issue(7)：978-980,3.DOI:10.3969/j.issn.1009-5519.2016.07.006
安徽省黄山市抗微生物药物不良反应报告1055例综合分析
Analysis of 1055 cases of adverse drug reaction caused by anti-microbacterial drugs in Huangshan City of Anhui ;Province
摘要
Abstract
Objective To analyze the reports of adverse drug reactions (ADR) caused by anti-microbacterial drugs from multiple hospitals in Huangshan City of Anhui Province during 2011-2013 and to summarize the data characteristics in order to reduce the ADR occurrence and promote the clinical safe and rational use of drugs. Methods A total of 1 055 cases of ADR re-port were collected in Huangshan City during 2011-2013. By using the ADR comprehensive analysis system (ADRCAS),the report data were analyzed in the aspects of the age,gender,type of involved drug and drug delivery route. Results Most of ADR caused by antimicrobial drugs in Huangshan City during 2011-2013 occurred in the age period of 40-<50 years old[22.27%(235/1 055)], most of involved organs or systems were the gastrointestinal tract system was[36.21%(382/1 055)],followed by skin and its acces-sories[23.22%(245/1 055)];amoxillin,azithromycin and roxithromycin had the highest ADR occurrence rate,which were 26.59%(271/1 055),19.53%(206/1 055) and 16.49%(174/1 055)respectively. Conclusion In the clinical treatment process of an-timicrobial drugs,the treatment effects should be paid high attention to,also their caused ADR should be highly alert, paying at-tention to safety and rationality of clinical medication.关键词
抗菌药/副作用/药物利用/药物副反应报告系统/药物监测/给药系统/药用制剂/副作用Key words
Anti-bacterial agents/adverse effects/Drug utilization/Adverse drug reaction reporting systems/Drug monitoring/Medication systems/Pharmaceutical preparations/adverse effects引用本文复制引用
胡骅,汤大娟,谢海棠,李静,陈雪,刘珍妮,杨晓蕾..安徽省黄山市抗微生物药物不良反应报告1055例综合分析[J].现代医药卫生,2016,32(7):978-980,3.基金项目
2014年皖南医学院大学生科研资助项目（WK2014S20）。 （）
