疑难病杂志2016，Vol.15Issue(5)：449-452,4.DOI:10.3969/j.issn.1671-6450.2016.05.003
液体营养餐负荷试验评估功能性消化不良患者胃感觉功能的研究
The investigation of liquid nutrient load test for the evaluation of functional dyspepsia
摘要
Abstract
Objective To analyze the correlation between liquid nutrient load test ( LNLT) and the gender, subtype in functional dyspepsia ( FD) patients.Methods A total of 44 patients from China Japan Friendship Hospital were enrolled and gender, age and subtype were recorded.Then all patients received the LNLT and recorded the threshold volume ( TV) and maximal volume (MV).Results A total of 44 patients (22 males and 22 females) have completed the trial.The patients were divided into 2 subtypes (17 cases in EPS, 27 cases in PDS).There were 44 healthy control group, 22 females and 22 males.TV of FD were lower than TV of healthy control group[(229.7 ±95.4)ml vs (269.8 ±36.1)ml, t =-2.609, P =0.012],MV of FD were lower than MV of healthy control group[(506.1 ±220.2)ml vs (755.9 ±79.9)ml, t =7.073, P <in FD were lower than TV of males in HS[(584.9 ±256.4)ml vs.(800.9 ±80.6)ml, t =3.770, P =0.001].MV of fe-males in FD were lower than TV of females in HS[(427.3 ±143.4)ml vs.(710.9 ±48.3)ml, t =8.792, P <0.01].TV of males were higher than TV of females[(194.6 ±81.8)ml vs.(264.8 ±96.7)ml, t =-2.601, P =0.013].MV of males were higher than MV of females[(427.3 ±143.4)ml vs.(584.9 ±256.4)ml, t =-2.517, P =0.016].There were 17 patients in subtype of EPS and 27 patients in subtype of PDS.There was no significant difference in TV and MV between EPS and PDS.TV of females in PDS were lower than TV of females in EPS[(156.2 ±63.6) ml vs.(238.0 ±80.3) ml, t =3.165, P =0.005], MV of females in PDS were lower than MV of females in EPS[(373.1 ±117.7) ml vs.(493.0 ± 143.9)ml, t =2.348, P =0.029].There was no significant difference in TV and MV between males and females in EPS.TV of females were lower than TV of males in PDS [(156.2 ±63.6)ml vs.(262.5 ±107.8)ml, t =3.018, P =0.005].MV of females were lower than MV of males in PDS[(373.1 ±117.7) ml vs.(568.1 ±222.0) ml, t =-2.711, P =0.009]. Early satiation was significantly related to MV ( r =0.236, P =0.048).Other symptoms were not related to TV and MV. Conclusion Gastric impaired accommodation appeared in FD patients.The function of gastric sensation was influenced by gender.The function of gastric sensation was not different between EPS and PDS, as well as between different symptoms.关键词
功能性消化不良/液体营养餐负荷试验/上腹痛综合征/餐后不适综合征Key words
Functional dyspepsia/Liquid nutrient load test/Epigastric pain syndrome/Postprandial distress syndrome引用本文复制引用
王慧芬,姚树坤,刘芳,杜时雨,王淼,张艳丽..液体营养餐负荷试验评估功能性消化不良患者胃感觉功能的研究[J].疑难病杂志,2016,15(5):449-452,4.基金项目
国家科技部“十二五”支撑计划 （）
