中国临床药理学杂志2016，Vol.32Issue(6)：526-528,3.DOI:10.13699/j.cnki.1001-6821.2016.06.015
罗哌卡因与布比卡因对剖宫产手术腰－硬联合麻醉患者血流动力学的影响
Influences of ropivacaine and bupivacaine on hemodynamic in patients undergoing cesarean section with spinal-epidural anesthesia
摘要
Abstract
Objective To investigate the effects of ropivacaine and bupivacaine on hemodynamic in patients undergoing cesarean section with spinal-epidural anesthesia.Methods A total of 98 pregnant women undergoing elective cesarean section were randomly divided into treatment group (49 cases) and control group (49 cases).The treatment group was received 0.75% ropivacaine 1.5 mL.Control group was received 0.75%bupivacaine 1.5 mL.The hemodynamic level, the effect of anes-thesia and the incidence of adverse drug reactions were compared between the two groups.Results Mean arterial pressure and systolic blood pres-sure in the treatment group were significantly higher than those in control group at 5 and 10 min after anesthesia ( P <0.05 ).In the treatment group, the sensory level and motor block were significantly longer than those of control group ( P<0.05).The time of sensory block and motor block in the treatment group were significantly less than those in control group ( P<0.05 ).There was no significant difference in the incidence of adverse reactions between the two groups ( P >0.05 ) .Conclusion Ropivacaine and bupivacaine for caesarean section are safe and effective, but ropivacaine has less hemodynamic disturbances and short duration of sensory level block and motor block, and therefore more contribute to recovery.关键词
罗哌卡因/布比卡因/剖宫产/腰-硬联合麻醉/血流动力学Key words
ropivacaine/bupivacaine/cesarean section/spinal-epidural anesthesia/hemodynamics分类
医药卫生引用本文复制引用
程英莉,吴建平,卢银军,俞芸芸,徐萌艳..罗哌卡因与布比卡因对剖宫产手术腰－硬联合麻醉患者血流动力学的影响[J].中国临床药理学杂志,2016,32(6):526-528,3.基金项目
浙江省医药卫生科技计划基金资助项目 （）
