中国临床药理学杂志2016，Vol.32Issue(7)：591-593,3.DOI:10.13699/j.cnki.1001-6821.2016.07.005
妊娠期糖尿病与脂肪细胞因子的关系
Relationship between gestational diabetes mellitus and adipocytokines
摘要
Abstract
Objective To study the relationship between gestational diabetes mellitus and adipocytokines.Methods Eighty patients with gestational diabetes mellitus were used as the case group, then divided into treatment group (n=40) and control group (n=40).And 80 cases of healthy women as the healthy control group were included in the same period. The treatment group was given comprehensive nutrition intervention, the control group was given conventional nutrition intervention, and the healthy control group did not give any treatment.Detection of serum fat factor and blood glucose metabolism in three groups were performed by automatic biochemistry analysis.Results Before intervention, the serum adiponectin and visfatin levels in treatment group and control group were lower than those of healthy control, the serum leptin, resistin, and retinol binding protein 4 in treatment group and control group were higher than those of healthy con-trol group ( P <0.05 ).After intervention, the serum adiponectin and visfatin in treatment group were significantly higher than those of control group, leptin, resistin and retinol binding protein 4 in treatment group were significantly lower than those of control group ( P <0.05 ).The fasting blood glucose, postprandial blood glucose and insulin resistance indexes in treatment group were significantly lower than those of control group ( P <0.05 ).Conclusion Serum adipocytokines contents in gestational diabetes mellitus patients are abnormal; comprehensivenutrition intervention is helpful to regulate adipocytokines content and glucose metabolism.关键词
妊娠期糖尿病/脂肪细胞因子/营养干预/血糖代谢Key words
gestational diabetes mellitus/adipocytokines/nutrition intervention/blood glucose metabolism分类
医药卫生引用本文复制引用
王秀艳,董艳..妊娠期糖尿病与脂肪细胞因子的关系[J].中国临床药理学杂志,2016,32(7):591-593,3.基金项目
东营市自然科学基金资助项目 （）
