阿立哌唑联合奥氮平治疗老年阿尔茨海默病伴精神障碍的临床疗效及安全性评价OA北大核心CSCDCSTPCD
Clinical efficacy and safety of aripiprazole combined with olanzapine in the treatment of elderly Alzheimer’ s disease with mental disorders
目的：观察阿立哌唑联合奥氮平治疗老年阿尔茨海默病伴精神障碍的临床疗效及安全性。方法将80例老年阿尔茨海默病伴精神障碍患者随机分为对照组40例和试验组40例。对照组予以口服奥氮平2.5 mg，每晚一次；试验组予以口服奥氮平2.5 mg，每晚一次联合阿立哌唑2.5 mg，每晚一次。2组患者一个疗程均为2周，共治疗4个疗程。比较2组患者的临床疗效、简易智能精神状态表（MMSE）评分、临床失智表（CDR）评分、日常生活能力表（ADL）评分、阿尔茨海默病评…查看全部>>
Objective To evaluate the clinical efficacy and safety of aripiprazole combined with olanzapine in the treatment of elderly Alzhei-mer’s disease with mental disorders.Methods Eighty patients of elder-ly Alzheimer’ s disease with mental disorders were randomly divided into treatment group ( n=40) and control group ( n=40).Patients in control group were received olanzapine 2.5 mg, oral, qn.Patients in treatment group were given olanzapine 2.5 mg, oral, qn and …查看全部>>
付旭;秦晓霞
中国医科大学 附属第一医院 心理科，沈阳110000中国医科大学 附属第一医院 心理科，沈阳110000
医药卫生
阿立哌唑奥氮平阿尔茨海默病精神障碍
aripiprazoleolanzapineAlzheimer’ s diseasemental disorder
《中国临床药理学杂志》 2016 (7)
应激、抗抑郁治疗对结直肠癌伴抑郁症患者心身康复作用的前瞻性研究
609-611,3
国家自然科学基金资助项目（81472853）
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