中国社区医师2016，Vol.32Issue(13)：61-62,2.DOI:10.3969/j.issn.1007-614x.2016.13.35
孕晚期注射乙肝免疫球蛋白对乙肝病毒母婴传播的阻断效果
Blocking effect of hepatitis B immunoglobulin injected at late pregnancy for mother to child transmission of hepatitis B virus
摘要
Abstract
Objective:To explore the blocking effect of hepatitis B immunoglobulin injected at late pregnancy for mother to child transmission of hepatitis B virus.Methods:150 cases of pregnant women were selected.The serum HBsAg and HBeAg of all pregnant women were positive.They were divided into the control group with 76 cases and the observation group with 74 cases.The pregnant women in the observation group during pregnancy were given hepatitis B immunoglobulin by injection.The pregnant women in the control group were not given hepatitis B immunoglobulin intervention.We compared the effect between groups. Results:At 6 months of birth,the HBsAg positive rate of the observation group of 2.6% was lower than 23% of the control group;the positive rate of HBsAb in the observation group of 44.7% was higher than 33.8% in the control group;the differences were statistically significant(P<0.05).At 12 months of birth,the HBsAg positive rate of the observation group of 2.6% was lower than 20.3% of the control group;the positive rate of HBsAb in the observation group of 55.3% was higher than 39.2% in the control group;the differences were statistically significant(P<0.05).Conclusion:Hepatitis B immunoglobulin injected at late pregnancy can effectively block the intrauterine infection.It may be an effective measure to be vaccinated with hepatitis B vaccine among women of childbearing age.关键词
乙肝免疫球蛋白/乙肝病毒母婴传播/阻断效果Key words
Hepatitis B immunoglobulin/Mother to child transmission of hepatitis B virus/Blocking effect引用本文复制引用
孔祥芹..孕晚期注射乙肝免疫球蛋白对乙肝病毒母婴传播的阻断效果[J].中国社区医师,2016,32(13):61-62,2.
