中国中医药信息杂志2016，Vol.23Issue(5)：83-86,4.DOI:10.3969/j.issn.1005-5304.2016.05.021
正交试验法优选定痛宁颗粒的乙醇提取工艺
Optimization of Ethanol Extraction Technology forDingtongning Granule by Orthogonal Design
张雷 1丁安伟2
作者信息
- 1. 南京中医药大学昆山附属医院，江苏昆山 215300
- 2. 南京中医药大学，江苏南京 210023
- 折叠
摘要
Abstract
Objective To optimize ethanol extraction technologyDingtongning Granule.Methods With yield of extract and content of tanshinoneⅡA as comprehensive evaluation indexes, the concentration of ethanol, the amount of ethanol, soaking time, extraction time and extraction times were selected as observing factors. Orthogonal design test L18(37) was used to optimize ethanol extraction technology ofDingtongning Granule.Results Optimum extraction conditions were as follows: soaking medicine for 0 hour; 2 times with 6 times of the amount of 80% ethanolre; flux extracted 3 hours each time.Conclusion This optimal extraction technology is stable and reliable, which can provide basis for industrial production ofDingtongning Granule.关键词
定痛宁颗粒/醇提工艺/丹参酮ⅡA/正交试验Key words
Dingtongning Granule/ethanol extraction technology/tanshinoneⅡA/orthogonal design分类
医药卫生引用本文复制引用
张雷,丁安伟..正交试验法优选定痛宁颗粒的乙醇提取工艺[J].中国中医药信息杂志,2016,23(5):83-86,4.
