中华灾害救援医学2016，Vol.4Issue(4)：190-192,3.DOI:10.13919/j.issn.2095-6274.2016.04.003
人体呼出气中总挥发性有机物水平与呼吸系统疾病相关性研究
Research on the correlation between total volatile organic commpounds level in exhale gas and respiratory disease
刘静莎 1索爽 2高红梅 1陈文丽 1陈献 1张晔 1谭青海 1谷晔 1张健鹏1
作者信息
- 1. 100039 北京，武警总医院呼吸内科
- 2. 102300，北京门头沟区医院呼吸科
- 折叠
摘要
Abstract
Objective To explore the correlation between volatile organic conmpounds (VOCs) concentration in human exhale gas and disease, in order to direct early diagnosis of disease.Methods 100 cases of patients with respiratory diseases one a first grade tertiary hospital of Chinese People’s Armed Police Forces were selected as research subjects, and divided into four groups: lung cancer group (n=15), pneumonia group (n=55), pulmonary fibrosis group (n=15) and chronic obstructive pulmonary diseases (COPD) group (n=15);81 cases of healthy medical staff were selected as the control group. Total VOCs concentration in exhaled gas (labeled Pvoc) of all subjects were detected by photoionization detector (PID).Results Compared with the control group, Pvoc of lung cancer group (Z=-2.523,P=0.012), pneumonia group (Z=-4.281,P<0.001), pulmonary fibrosis group (Z=-3.204,P=0.001) and COPD group (Z=-2.644,P=0.008) were obviously decreased, the differences were all statistically significant. Comparison of Pvoc in any two groups of lung cancer group, pneumonia group, pulmonary fibrosis group and COPD group, there were no statistical significance.Conclusions Total VOCs concentration in exhale gas detected by PID has no contribution to the diagnosis of lung cancer, pneumonia, pulmonary fibrosis and COPD.关键词
挥发性有机物/呼吸系统疾病/光离子化探测器Key words
volatile organic compounds/respiratory disease/photoionization detector分类
医药卫生引用本文复制引用
刘静莎,索爽,高红梅,陈文丽,陈献,张晔,谭青海,谷晔,张健鹏..人体呼出气中总挥发性有机物水平与呼吸系统疾病相关性研究[J].中华灾害救援医学,2016,4(4):190-192,3.
