中华灾害救援医学2016，Vol.4Issue(4)：199-202,4.DOI:10.13919/j.issn.2095-6274.2016.04.006
不同预后积分系统在骨髓增生异常综合征预后评估中的对比
Comparative study on different prognostic scoring system in prognosis evaluation of myelodysplastic syndrome
摘要
Abstract
Objective To explore the significance among different scoring systems in predicting the prognosis of myelodysplastic syndrome (MDS), to guide the clinical accurate prognosis stratification and personal treatment.Methods The clinical data of 72 patients with newly diagnosed MDS were retrospectively reviewed, the prognosis was evaluated according to international prostate symptom score (IPSS), World Health Organization classification-based prognostic scoring system (WPSS) and revised international prognostic scoring system (IPSS-R). Results The difference of median survival time between different groups of prognostic scoring system was statistically significant (Tarone-Ware=9.572-19.834,P<0.05). The survival curve of WPSS had more intersections between each group, IPSS-R prognosis had less intersections. For low risk group, prognostic evaluation of IPSS and WPSS were poor, IPSS-R was the best way to predict the prognosis. Correlation between IPSS and IPSS-R was the strongest (rs=0.765,P<0.05).Conclusions All the three scoring systems can better predict the prognosis of patients with newly diagnosed MDS, and IPSS-R has more advantages. Integrated using 3 scoring system in clinical work is more favorable for clinical prognosis evaluation of MDS.关键词
骨髓增生异常综合征/预后积分系统/生存分析Key words
myelodysplastic syndrome/prognostic scoring system/survival analysis分类
医药卫生引用本文复制引用
王薇,吴广胜..不同预后积分系统在骨髓增生异常综合征预后评估中的对比[J].中华灾害救援医学,2016,4(4):199-202,4.基金项目
石河子大学医学院第一附属医院院级课题 （）
