肿瘤药学2016，Vol.6Issue(2)：96-102,7.DOI:10.3969/j.issn.2095-1264.2016.02.03
前列腺癌发生发展相关信号转导通路的研究进展
Advances in the Signal Transduction Pathway Related to the Development of Prostate Cancer
申利贤 1周斌 1李海艳 1闵可 1蒋敏媚 1郭玉1
作者信息
- 1. 南华大学药物药理研究所，湖南省分子靶标新药研究协同创新中心，湖南 衡阳，421001
- 折叠
摘要
Abstract
The development and progression of prostate cancer is a complex process. Abnormalities in the intracellular signaling pathway are important mechanisms in the development and progression of prostate cancer. Previous studies have demonstrated that the Hedgehog signaling pathway, WNT signaling pathway, Notch signaling pathway and MAPK signaling pathway played important roles in prostate cancer development, progression and metastasis. In this paper, we made a brief summary on the relevant signal transduction pathway in the occurrence and development of prostate cancer, expecting to pro-vide new targets, techniques and means for preventing and early diagnosing and treating of prostate cancer.关键词
前列腺癌/Hedgehog 信号通路/Wnt 信号通路/Notch 信号通路/MAPK 信号通路Key words
Prostate cancer/Hedgehog signaling pathway/WNT signaling pathway/Notch signaling pathway/MAPK signaling pathway分类
医药卫生引用本文复制引用
申利贤,周斌,李海艳,闵可,蒋敏媚,郭玉..前列腺癌发生发展相关信号转导通路的研究进展[J].肿瘤药学,2016,6(2):96-102,7.
