安徽医科大学学报2016，Vol.51Issue(4)：569-573,5.
目标导向液体治疗在老年膀胱癌根治术的临床研究
Clinical research of goal-directed fluid therapy in elderly patients with radical resection of bladder cancer
摘要
Abstract
Objective To investigate clinical studies in elderly bladder carcinomaradical resection treatment goal directed fluid. Methods Seventy-six elderly patients with radical resection of bladder cancer were selected who were randomly divided into two groups. 38 patients received routine treatment as group I. Based on routine treat-ment, 38 patients received goal-directed fluid therapy as groupⅡ. Treatment effect was compared between the two groups. Results Cardiac index(CI), stroke volume variation(SVV), mean arterial pressure(MAP), central ve-nous pressure(CVP), central venous oxygen saturation(ScvO2), oxygen supply index(DO2I), oxygen consump-tion index( VO2 I) , oxygen uptake rate( ERO2 ) were significantly higher in groupⅡthan those in groupⅠat T1 , T2 , T3 , T4 , while lactate( Lac) , S100βwere significantly lower in group II than those in groupⅠat T1 , T2 , T3 , T4 . The urine volume and colloidal infusion were significantly more in group Ⅱthan those in group Ⅰat T1 , T2 , T3 , T4 , while the crystalloid infusion volume, total liquid infusion volume, hospitalization time and expenses were significantly less in group Ⅱ than those in groupⅠ, while the complication incidences of nausea, vomiting or hy-potension were significantly lower in group Ⅱ than those in group Ⅰ. The postoperative first passage of flatus and postoperative food-taking time were significantly earlier in groupⅡthan those in groupⅠ( P<0. 05 ) . Conclusion Goal-directed fluid therapy is beneficial for stabilization of hemodynamic status, maintenance of oxygen balance of supply and demand, as well as rapid postoperative recovery in elderly patients with radical resection of bladder cancer.关键词
老年/膀胱癌根治术/目标导向液体/临床效果Key words
older/radical resection of bladder cancer/goal-directed fluid/clinical effect分类
医药卫生引用本文复制引用
刘铁军,蒲国华,程爱斌,王建军,高晓增,白净,张树波,董晓柳..目标导向液体治疗在老年膀胱癌根治术的临床研究[J].安徽医科大学学报,2016,51(4):569-573,5.基金项目
河北省高等学校科学技术研究指导项目(编号:Z2015006) （编号:Z2015006）
2015年河北省政府资助临床医学优秀人才项目 （）
