安徽医科大学学报2016，Vol.51Issue(4)：598-600,3.
胰腺癌缺失基因DPC4在牙龈癌中的表达
Expression of deleted in pancreatic cancer 4 in gingival cancer
摘要
Abstract
To observe the expression of DPC4 in gingival cancer tissue, the expression of protein and mRNA in 33 cases of gingival cancer and 8 cases of normal gum tissue were investigated by immunohistochemistry and Real-time PCR. Results showed that the positive cell rate of DPC4 in gingival cancer was lower than that in normal gum tis-sue. The expression of DPC4 and the expression of mRNA protein showed significant differences in well-differentia-ted, moderately differentiated, poorly differentiated gingival cancer and normal gum tissue(P<0. 05). The expres-sion of DPC4 in normal gum tissue is significantly higher than that in various differentiation types of gingival cancer tissue.关键词
胰腺癌缺失基因4/牙龈癌/免疫组织化学/Real-time PCRKey words
DPC4/gingival cancer/immunohistochemistry/Real-time PCR分类
医药卫生引用本文复制引用
张强,刘继刚,杨国海,刘江,刘昊..胰腺癌缺失基因DPC4在牙龈癌中的表达[J].安徽医科大学学报,2016,51(4):598-600,3.基金项目
河北省2015年度医学科学研究重点课题计划项目(编号:20150087) （编号:20150087）
