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急性缺血性脑卒中患者重度脑白质病变的危险因素分析

曹林 张美芳 胡旻婧 沈丽华

重庆医学2016,Vol.45Issue(11):1526-1527,1530,3.
重庆医学2016,Vol.45Issue(11):1526-1527,1530,3.DOI:10.3969/j.issn.1671-8348.2016.11.025

急性缺血性脑卒中患者重度脑白质病变的危险因素分析

The risk factors of severe white matter lesions in acute ischemic stroke

曹林 1张美芳 1胡旻婧 1沈丽华1

作者信息

  • 1. 南通大学附属医院神经内科,江苏南通226000
  • 折叠

摘要

Abstract

Objective To investigate the incidence of white matter lesions(WML) in acute ischemic stroke ,and to analyze its the risk factors .Methods Totally 248 cases of acute ischemic stroke patients were selected ,patients′general information were in‐vestigated ,the WML severity with Fazekas rating scale were evaluated and patients were divided into severe group and no severe group according to the results ,the differences of general information between two groups were compared ,the severe WML was set as dependent variable ,the risk factors were ananlzed by multiariable Logistic regression analysis .Results There were 106 cases se‐vere WML patients among 248 cases acute ischemic stroke ,the incidence was 42 .74% ;single factor analysis found that the age in severe group was significantly higher than non severe group ,the incidence of hypertension ,diabetes in severe group was significantly higher than non severe group ,the difference was statistical significance (P<0 .05);multiariable Logistic regression analysis showed that age (OR=4 .116 ,95% CI:1 .816-6 .454 ,P=0 .000) ,hypertension (OR=1 .462 ,95% CI:0 .842-1 .946 ,P=0 .026) and dia‐betes (OR=1 .157 ,95% CI:0 .698-1 .673 ,P=0 .038)were the independent risk factors of severe WML in acute ischemic stroke . Conclusion The incidence of severe WML in acute ischemic stroke patients is high ,we need to targeted prevention measures on ol‐der age ,hypertension ,diabetes mellitus patients to reduce severe WM L occurred .

关键词

缺血性脑卒中/脑白质病变/严重程度/危险因素

Key words

ischemic stroke/white matter lesions/severity/risk factors

分类

医药卫生

引用本文复制引用

曹林,张美芳,胡旻婧,沈丽华..急性缺血性脑卒中患者重度脑白质病变的危险因素分析[J].重庆医学,2016,45(11):1526-1527,1530,3.

重庆医学

OA北大核心

1671-8348

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